Additive manufacturing (AM) has become increasingly relevant in global manufacturing, offering a cost-effective and straightforward way to produce complex parts that are difficult to achieve using conventional methods. However, issues such as dimensional accuracy and surface quality of AM-manufactured parts often require post-processing, highlighting the importance of machining in the production line. In the case of Wire and Arc Additive Manufacturing (WAAM), these challenges are even more pronounced, once the method uses high thermal inputs to create metal parts with overlapping layers, which can lead to anisotropy and discontinuities. Therefore, considering the anisotropic characteristics of AM metals, this study investigates how the cutting path angle influences the surface quality after end milling of parts manufactured with ER70S-6 wire. For this purpose, a carbide milling cutter with titanium aluminum nitride (TiAlN) coating, with a diameter of 5 mm and four cutting edges, and five different cutting angles, ranging from 0° to 90° in 15° increments, was used. The analyses revealed that the slots milled at 45° presented the best surface quality and lowest average roughness value Rq = 0.22 µm, while the slots at 15° had the worst qualitative and quantitative results, Rq = 0.53 µm. It was concluded that cutting angles greater than 45° produce better quality machined surfaces compared to lower angles, becoming the best recommendation for milling parts manufactured by WAAM.