The paper identifies links between the recent reform of the Italian taxation system, which began with the tax reform enabling law no. 111 of 9 August 2023, and megaprojects. Particular attention is paid to the effects that an initial evaluation suggests have been triggered for entities intending to commit to megaprojects following reform of the tax residence of legal entities, changes to the rules governing the controlled foreign company (CFC) tax regime, introduction of the global minimum tax into the Italian legal system, the anticipated application of measures to incentivize reshoring and, finally, changes to the cooperative compliance regime.