Technological advancement and the increase in the consumption of natural resources have generated a growing volume of waste, especially in the forestry sector. The production of agglomerated panels from wood waste and the use of vegetable resins, such as those derived from castor oil, emerge as sustainable alternatives to mitigate the environmental impacts caused by the improper disposal of these materials and the development of environmentally friendly materials. The objective of this study was to evaluate the feasibility of producing agglomerated panels of wood particles from waste of angelim-ferro (Dinizia excelsa), cupiúba (Goupia glabra) and cedar with caferana (Cedrela spp and Erisma uncinatum), using vegetable polyurethane resin based on castor oil. Water absorption, flexural rupture (MOR) and screw pullout tests were performed to characterize the physical-mechanical properties of the panels. The results indicated that the panels produced presented densities ranging between 0.75 and 0.92 g/cm3, classifying them as medium and high density. The values of flexural strength and screw pullout met the Brazilian (NBR), American (ANSI) and European (EN) technical standards, demonstrating potential for application in ceiling panels. It was observed that the use of these wood wastes, combined with vegetable resin, is a viable and sustainable alternative to produce construction materials, contributing to the reduction of environmental impacts.