As part of the transition to a more sustainable future, more and larger multi-storey timber buildings are being realised. Simultaneously, the frequency and magnitude of potential hazards have been increasing. Therefore, the resistance of timber buildings to disproportionate collapse is becoming increasingly relevant. However, current robustness guidelines to limit disproportionate collapse were developed for reinforced concrete and steel buildings and are inappropriate for timber buildings. Consequently, there is an urgent need to bridge the knowledge gap on the robustness of timber buildings. To investigate the robustness of buildings, it is common to assess single-column damage scenarios on the ground-floor. However, recent research has shown that relevant damage scenarios are not limited to ground-floor damage. Various hazards, such as vehicle impact and far-field blast loading, may entail damage to multiple columns. To address these knowledge gaps, this paper presents a case study of a timber frame building subjected to single- and multi-column damage scenarios. A damage assessment and sensitivity analyses were conducted, where the societal and material consequences were quantified based on the life quality index. The analyses are conducted using a recently developed framework for modelling progressive collapse of inelastic building structures using nonlinear dynamic analysis.