Although Oman has established a sophisticated digital health infrastructure, adopting health technology remains suboptimal. This study applies the Unified Theory of Acceptance and Use of Technology (UTAUT) framework, integrating Oman-specific cultural dimensions—such as trust in authority and conformity to societal norms—to address non-technical barriers to technology uptake. By exploring critical behavioral drivers, including performance expectancy, effort expectancy, social influence, and facilitating conditions, this research tailors the UTAUT model to Oman’s healthcare context through a comprehensive literature review. The findings reveal that socio-cultural factors significantly influence technology acceptance, providing valuable insights for policymakers to design culturally resonant training and awareness programs. While future empirical validation through surveys and interviews is required, this framework offers a structured pathway for Omani healthcare practitioners to develop digital health interventions aligned with local cultural values. By centering on Oman’s unique socio-cultural context, this study contributes to the UTAUT literature, advancing the nation’s Vision 2040 objectives and Sustainable Development Goal 3 (Good Health and Well-being). These insights promote a more inclusive healthcare transformation, fostering a digital health ecosystem that aligns with Oman’s cultural and societal framework.