In the present work, experiments are conducted to characterize 3D-printed structures under bending loading. Special emphasis is placed on printing with the material PET-G (Polyethylene Terephthalate Glycol), known for its excellent mechanical properties, such as impact and puncture resistance, making it a durable and robust material. The selection of PET-G is considered significant, as it is suitable for applications requiring strong and long-lasting components. A key focus of the study is the investigation of how different printing parameters affect the mechanical performance of the printed structures. The experiments are designed and conducted using the Taguchi method, which enables efficient optimization of multiple parameters. PET-G structures are printed under varying settings, such as printing angle, layer height, line width, printing temperature and printing speed, following Taguchi’s orthogonal array, allowing for a systematic analysis of how these factors influence the material’s bending behavior. By combining analytical modeling with the experimental results obtained through the Taguchi approach, a deeper understanding is achieved regarding the effects of the 3D printing process on the mechanical properties of PET-G-printed structures. This method provides valuable insights into optimizing printing parameters, leading to improved mechanical performance in real-world applications.