The Sino-Himalayan region is recognized as the world’s largest floristic center of Rhododendron plants, contributing instrumental ornamental Rhododendron germplasm to Western horticultural sectors and thereby significantly enhancing the species’ cultivation and breeding techniques. The region is also the cradle of the flower-eating culture of Rhododendron, with all resources utilized being of wild origin. This fact is unexpected, given that numerous Rhododendron species are commonly known to be poisonous. In this study, we explored the typical motivators of the consumption of Rhododendron flowers in the region by conducting a field survey in Southwest China and a literature survey of cases from the remaining areas. The results showed that the consumption of Rhododendron flowers, including using them as vegetables or ingredients in pastries, drinks, and sauces, is widely shared by the areas with resource distribution. The motivators include gastronomic tour development, indigenous economic benefits, and local food culture rooted in traditions. The commercial trends of both collection and processing of the flowers facilitate the large quantities of consumption of some Rhododendron flowers. This study identifies the Rhododendron flower as a distinctive element within the culinary culture of the Sino-Himalayan region and its surroundings, thereby enhancing our understanding of the ecological product value of edible Rhododendron flowers.