The paper explores the concept of “studentification,” which refers to the urban changes that occur because of a growing concentration of university students in specific neighborhoods. While this trend can benefit local economies, it poses significant socio-economic, demographic, and urban planning challenges. The case study focuses on the University of Calabria (UNICAL) and demonstrates how the increasing student population has affected the rental market in nearby areas, particularly in the Quattromiglia neighborhood. A survey was conducted targeting UNICAL students to study their housing preferences, and 525 valid responses were analyzed. Econometric analyses, including the Appraisal System Model and Multiple Regression Models, were used to assess how various property characteristics, such as proximity to the university, availability of services, and parking, impact rental prices. The results indicate that the student population significantly influences housing prices and availability, leading to imbalances in the rental market. Other key findings reveal that student preferences, such as proximity to services, availability of parking, and nightlife, significantly impact rental prices. Additionally, the paper explores the broader impacts of studentification on property sales prices, noting a decrease in residential property values in heavily student-populated areas. The findings suggest the need for urban planning strategies that harmonize the needs of students and permanent residents, proposing regulations and collaboration between universities and local governments to mitigate negative impacts.