Accurately detecting 3D objects from monocular images in dynamic roadside scenarios remains a challenging problem due to varying camera perspectives and unpredictable scene conditions. This paper introduces a two-stage training strategy to address these challenges. Our approach initially trains a model on the large-scale synthetic dataset, RoadSense3D, which offers a diverse range of scenarios for robust feature learning. Subsequently, we fine-tune the model on a combination of real-world datasets to enhance its adaptability to practical conditions. Experimental results of the Cube R-CNN model on challenging public benchmarks show a remarkable improvement in detection performance, with a mean average precision rising from 0.26 to 12.76 on the TUM Traffic A9 Highway dataset and from 2.09 to 6.60 on the DAIR-V2X-I dataset, when performing transfer learning. Code, data, and qualitative video results are available at https://roadsense3d.github.io .