Organ regeneration through regenerative medicine is very important in the future sustainable health care systems because it can offer new treatment solutions for the damaged tissues and organs rather than relying on organ transplantation. It has the ability of addressing issues in the long-term and reduce on the frequency of the interventions. This interdisciplinary field concerns the use of concepts derived from stem cell biology, tissue engineering and material science in order to produce therapies that offer the functionality and architecture of the natural tissue. Stem cell research is at the forefront of regenerative medicine because they provide information on optimizing tissue and organ regeneration as well as developing new treatment approaches for numerous diseases. Tissue engineering makes the development of biological substitutes for helping damaged tissues and organs, where scaffold material design plays a vital role. Most regenerative treatments are outpatient procedures, making it easy for doctors to tailor the treatment to help boost the efficiency of the intervention, shorten the healing period, and reduce susceptibility to post-surgical complications. There are innovative biomaterials, new cell origin, and tissue engineering technologies. Regenerative medicine can be aligned with sustainable healthcare as it provides long term effective solutions since people do not have to visit the hospital frequently over and over again, enhance patients’ quality of life and decrease the prevalence of chronic diseases. The thoughtful transition to applied regenerative medicine defines the new efficient and sustainable trend in the healthcare system.