Why should you review grants? A cornerstone of any academic career is academic citizenship. This includes a broad range of activities from sustaining scientific integrity to participation in enterprises such as mentorship and manuscript and grant reviewing. Each year, hundreds of thousands of grant applications are received by the National Institutes of Health, Veterans Administration, National Science Foundation, foundations, state, and other granting agencies in the field of clinical and biomedical research. As a result, there is a substantial need for experienced experts to review each of these grants. For new academic investigators, this potential opportunity raises a number of key issues. When is it appropriate for me to begin reviewing grants? Is there any benefit to my own career development by reviewing grants? How would I go about obtaining opportunities to review grants? Are there guidelines for how to best review a grant? The goal of this chapter is to address these key questions.