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Spitz nevus and its pigmented variant, Reed nevus, are benign melanocytic neoplasms characterized by a proliferation of large spindle and/or epithelioid cells. They most frequently occur within the first two decades of life. Classical Spitz nevus is a solitary, asymptomatic, amelanotic, or hypopigmented papule or, less frequently, a nodule, a plaque, or a polypoid formation. The pigmented variant clinically presents as a solitary, dark brown to black papule or plaque. Six main dermatoscopic patterns can be ascribed to Spitz/Reed nevus: the “vascular pattern,” the “starburst pattern,” the “globular pattern,” the “homogenous pattern,” the “reticular pattern,” and the “melanoma-like” pattern.

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Spitz/Reed Nevus

  • 章节

  • 发表日期：

    2025年

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  • Eugenia Veronica Di Brizzi,
  • Graziella Babino,
  • Elvira Moscarella,
  • Elisabetta Fulgione,
  • Elena De Col,
  • Vincenzo Piccolo,
  • Giuseppe Argenziano

摘要

Spitz nevus and its pigmented variant, Reed nevus, are benign melanocytic neoplasms characterized by a proliferation of large spindle and/or epithelioid cells. They most frequently occur within the first two decades of life. Classical Spitz nevus is a solitary, asymptomatic, amelanotic, or hypopigmented papule or, less frequently, a nodule, a plaque, or a polypoid formation. The pigmented variant clinically presents as a solitary, dark brown to black papule or plaque. Six main dermatoscopic patterns can be ascribed to Spitz/Reed nevus: the “vascular pattern,” the “starburst pattern,” the “globular pattern,” the “homogenous pattern,” the “reticular pattern,” and the “melanoma-like” pattern.