Dermatoscopy (or dermoscopy) is a simple technique that allows a noninvasive, magnified, in vivo visualization of microstructures of the skin (epidermis, dermo-epidermal junction, and papillary dermis) not visible to the naked eye. The most used device is the handheld dermatoscope that is user-friendly and relatively inexpensive Dermatoscopy requirements include a high-quality lens for ×10 magnification and a transilluminating lighting system, typically using an incident light source or a cross-polarized light. Videodermatoscopes are more expensive computer-assisted digital systems that may be equipped with lenses that ensure higher magnifications, up to ×1000. Videodermatoscopes can also be equipped with systems able to arrange automatic computerized analysis of pigmented lesions.