This chapter describes a miniaturized 3-D magnetic resonance imaging (3-D-MRI) scanner empowered by a high-voltage silicon-on-insulator (HV-SOI) CMOS application-specific integrated circuit (ASIC). With a 0.52-T permanent magnet and integrating the electronics onto a 6-mm2 silicon chip, the scanner weighs 21 kg and provides a field of view (FOV) of 10 × 8 × 8 mm3 for probing the internal structure of a wide variety of objects non-invasively. The ASIC features a mixed-transistor HV-enabled transmitter (TX) to enhance the output-current deliverability (1.24 App to a 1-Ω load), a low-noise receiver (RX) exploiting the dynamic-threshold MOSFET (DTMOS), and deep trench isolation (DTI) for better noise performance and substrate noise immunity. The achieved RX input-referred noise of 0.63 nV/√Hz significantly enhances the SNR of the image and enables fast image acquisition. We also introduce a digital-to-analog converter (DAC)-based gradient controller to compose the MRI sequences for 3-D spatial encoding. The key functionality of the 3-D-MRI scanner is exhibited with two fruit samples: raspberry and pomegranate, achieving a resolution of 110 × 117 × 250 μm3, in 0.17 min.

错误:搜索内容不能为空,请输入英文关键词
错误:关键词超出字数限制,请精简
高级检索

A Miniaturized 3-D-MRI Scanner Featuring a High-Voltage SOI ASIC

  • Shuhao Fan,
  • Qi Zhou,
  • Ka-Meng Lei,
  • Rui P. Martins,
  • Pui-In Mak

摘要

This chapter describes a miniaturized 3-D magnetic resonance imaging (3-D-MRI) scanner empowered by a high-voltage silicon-on-insulator (HV-SOI) CMOS application-specific integrated circuit (ASIC). With a 0.52-T permanent magnet and integrating the electronics onto a 6-mm2 silicon chip, the scanner weighs 21 kg and provides a field of view (FOV) of 10 × 8 × 8 mm3 for probing the internal structure of a wide variety of objects non-invasively. The ASIC features a mixed-transistor HV-enabled transmitter (TX) to enhance the output-current deliverability (1.24 App to a 1-Ω load), a low-noise receiver (RX) exploiting the dynamic-threshold MOSFET (DTMOS), and deep trench isolation (DTI) for better noise performance and substrate noise immunity. The achieved RX input-referred noise of 0.63 nV/√Hz significantly enhances the SNR of the image and enables fast image acquisition. We also introduce a digital-to-analog converter (DAC)-based gradient controller to compose the MRI sequences for 3-D spatial encoding. The key functionality of the 3-D-MRI scanner is exhibited with two fruit samples: raspberry and pomegranate, achieving a resolution of 110 × 117 × 250 μm3, in 0.17 min.