Invited to answer the question, “How do gender/sex inform intersectional understandings of structural inequalities on health?” this chapter holds that the premise of the question is incorrect on two grounds. First, gender/sex and their entanglements do not inform intersectional understandings of structural inequalities on health; multiple and intersecting systems of structural oppression (e.g., racism, sexism, and cisgenderism) do. Second, it is impossible to separate gender/sex and their entanglements from other key intersectional positions such as racialized and sexual minoritized status. Using a structural intersectionality approach grounded in examples and data of Black and other racialized groups primarily in the United States, this chapter addresses the controversy of the single-axis assumption that gender/sex is, can, or should be disentangled from other key historically marginalized intersectional positions. It examines the unsolved problem of the relative absence of intersectionally specifc language (other than gendered racism) to describe the health inequities that groups, such as Black women, men, and transgender, nonbinary, and gender-expansive people, experience because of multiple and interlocking oppression based on their intersectionally distinct positions as Black women, Black men, and Black transgender, nonbinary and gender-expansive people.