This study aims to explore the potential approaches, factors, and tactics that can be applied to Industry 4.0. Further, it focuses on grouping those approaches that fully allow industries to achieve sustainable development. The United Nations’ Sustainable Development Goals (SDGs) is a common, shared, and open agenda that has been applied in industries. With the spice of Industry 4.0, it is easier for industrialists to implement the SDGs in true spirit and achieve the standards of sustainable development. Under the umbrella of scholarly findings, key insights are identified through influential aspects and conceptual analysis. At initial, the study grouped 1972 research findings, after filtration of other disciplines we finalized 1880 research attempts for further proceedings and analysis. We identified the top countries, authors, citation networks, and journals; thereby, we may able to compile the current practices and 4.0 strategies of those regions where they are already being applied. For conceptual analysis, we made an effort to construct the thematic map co-occurrence and keyword analysis. From conceptual analysis, this chapter identified the themes and subthemes, as well as potential, cost-efficient, and eco-friendly activities adopted by various industrial regions and zones. Its analytical findings revealed that the applications of Industry 4.0 have a substantial prospect for current survival, future growth, and competitiveness of businesses. To attain continuous growth, SDGs were built as a universal mechanism that is equally important for the product, process, and operational activities of all industries. Nowadays, Industry 4.0 has revolutionized regular working standards and has technologically controlled working tracks. To best deal with current and future challenges, this chapter is a robust guiding principle for government, current entrepreneurs, business firms, industrialists, and policymakers.