The effects of water contamination have been well demonstrated globally. Water quality is steadily declining as a result of urbanization, industry, and globalization, which is the main cause of health and environmental degradation. Numerous significant amounts of metals & metalloids (Ni, Pb, Cr, Hg, Cd, Cu, Zn, and As) have been found in water samples, raising concerns about water contamination on a worldwide scale. Because arsenic cannot biodegrade, an accumulation of it in biological systems can have harmful impacts on health. According to the US-ATSDR, arsenic ranks first and is a group “A” carcinogen among the hazardous ions list published in 2001. Different methods and materials have been applied to recover arsenic from different immerged water sources. Ion exchange, electrodialysis, membrane separation, chemical oxidation, and adsorption are the prime methods used for recovery of arsenic (As). Adsorption is one of the best methods for arsenic removal because of its low cost and easy handling. Synthetic, natural, and modified materials are effective adsorbents for arsenic removal. The Langmuir, Freundlich, and Temkin isotherms explained the removal mechanism of arsenic using various kinetic models (pseudo-first-order model & pseudo-second-order). The aim of this chapter is to explore the materials that have been used for the mitigation of arsenic from water. This study also compares the materials on the basis of their performance.