This chapter explores the multifaceted approach of Integrated Pest Management (IPM) in sustainable agriculture, emphasizing the importance of combining various pest control strategies. It highlights the role of biodiversity in enhancing natural pest controllers, cultural practices such as crop rotation and soil health management, and biological control methods involving natural predators and biopesticides. Furthermore, it addresses the responsible use of chemical pesticides and the need for pesticide resistance management. The integration of chemical and non-chemical methods forms the foundation of an effective IPM strategy, contributing to agricultural productivity while minimizing environmental impact. The chapter underscores the necessity of adopting IPM practices for a sustainable agricultural future.