The end-fixity and spacing between the piles influence the performance of the structures under seismic events. The present study investigates the influence of spacing of floating piles on the seismic performance of the building through experimental investigation. In this study, a scaled-down model supported on floating piles with varying spacing (S/D) is used. All these model tests are performed in the laminar container using a shake table, and the results obtained are validated using numerical analysis. All the models are subjected to sine sweep test, free vibration test, and scaled-down input motions. The seismic performance of the coupled system is represented in terms of the fundamental period. It is observed that the fundamental period of the system (S/D = 3, 45% relative density (RD)) has increased by 52.90% compared to the fixed base conditions. Additionally, it is found that the fundamental period of the system has reduced by 2.89% when the spacing between the piles increases from 3 to 6. The increase in the spacing between the piles enhances the overall stiffness of a pile group by avoiding the overlapping of stress bulbs. This increased spacing reduces mass participation, thus reducing the fundamental period.