The main aim of the present research is to examine the response of combined pile-raft foundation (CPRF) under static and dynamic loading. In this numerical study, a 3D Midas GTS NX software has been used to analyse axial load and settlement. Analysis has been done by varying different parameters—length of pile, thickness of raft and diameter of pile. The 3D model has been made by assigning material properties to different foundation components and soil through meshing. In case of high-rise buildings and difficult subsoil conditions, a piled-raft system is more efficient. The CPRF keeps the structure’s settlement, differential settlement, and tilting within the permitted limits by bearing high valued vertical load. This study examines the effectiveness of combined pile-raft foundations in elasto-plastic soil. The numerical result shows that enhancing the inertial impact by stiffening the CPRF by using raft thickness (tp) = 3 m, and spacing to diameter ratio (S/D) = 3, absorbs most of the earthquake’s energy.