For bridges located in seismic intensity zones of grade VII or higher, the seismic performance of the structure is a key focus in the design process. This article studies a high pier continuous rigid frame bridge, focusing on the friction pendulum seismic isolation bearings. The response spectrum method, time history analysis method, and nonlinear time history analysis method with friction pendulum support are used to compare the seismic response of the bridge structure, to verify the bearing capacity of the pier structure under earthquake conditions, and to explore the seismic performance of the continuous rigid frame bridge. The results indicate that friction pendulum seismic isolation bearings can extend the natural vibration period of bridge structures, reduce force response and displacement response under earthquake conditions, and effectively improve the seismic performance of bridges.