Carbon dioxide phase transformation cracking technology is a safe, efficient and green gas explosion technology. However, the standard design method of this technology in engineering application has not been put forward. According to the rock breaking mechanism of this technology, and combined with engineering experience, a design method was established. Rock mass quality coefficient Q was used to evaluate the rock mass, and the relationship between the suggested values of Q and energy consumption was summarized. The parameters of drilling, included depth, hole spacing and row spacing was clearly defined. Based on engineering test results, the design method has been confirmed. The experimental results show that this technology was a kind of vibration control and efficient method in excavation of rock mass. Q could effectively grade the site rock mass, and it was convenient for situation assessment and could determine the main parameters quickly. The maximum vibration velocity can be controlled under 20 mm/s at a distance of 10 m from the vibration source, which is suitable for rock excavation projects with high vibration control requirements.