With increasing plant biotic and abiotic stresses, there is a growing need for innovative strategies to increase plants’ tolerance to these stresses. To address some of the biotic and abiotic challenges, nanotechnology has come to light as a fascinating field of study with possible applications in agriculture. Numerous studies indicate that nanomaterials play roles in the management of plants’ stress. In recent times, large-scale production of nanoparticles and nanostructured materials has gained a lot of notice, as they are essential to several sectors, including the agricultural sector. Engineered nanomaterials have shown great potential in enhancing the growth and stress tolerance of plants under unfavorable conditions. Nanomaterials have unique properties that make them ideal tools for addressing plant stress tolerance. These properties include their small size, large surface area, high reactivity, and ability to penetrate plant tissues effectively. Furthermore, engineered nanomaterials interact with plants in specific ways, such as delivering nutrients or enhancing antioxidant capacity. Incorporating nanomaterials into plant systems has been found to enhance plant resistance to various abiotic stresses. The use of engineered nanomaterials helps to augment non-native properties in plants, leading to enhanced stress tolerance. In effect, engineered nanomaterials hold great promise for enhancing abiotic stress tolerance in plants. This chapter highlights the synthesis of nanomaterials and the significant potential of engineered nanomaterials in enhancing biotic and abiotic stress tolerance in plants.