The management of partially treated or untreated wastewater from seafood processing industries presents considerable challenges due to the negative impacts it poses on the environment and public health. This review article is aimed at providing a comprehensive analysis of the management practices associated with seafood wastewater. As seafood processing plays a vital role in global nutrition and food security, the generation of substantial amounts of wastewater containing various pollutants such as organic matter, nutrients, and suspended solids poses a serious concern. This article explores the challenges faced in seafood wastewater management and discusses the pollution potential, characteristics, technologies, strategies, and best practices that can effectively address these challenges. Adopting a holistic approach, this review covers topics such as wastewater production, environmental impacts, regulatory frameworks, remediation methods, and valuable resource recovery in sustainable management of seafood processing wastewater. The objective is to promote the development of sustainable, efficient, and best practices for wastewater management in the seafood processing industry, ensuring the protection of the environment and public health.