In the current context of rehabilitation for individuals with disabilities, myoelectric prostheses represent an advanced solution to improve mobility and functionality for individuals with upper limb amputations. However, the high costs associated with these prostheses significantly limit their accessibility, leaving many patients without viable and affordable options. This study presents the development of a low-cost myoelectric prosthetic hand prototype employing open-source hardware and software technologies. Key components include the Arduino Nano, Myoware sensors for capturing muscle signals, MG996 servomotors for precise movement, and a mobile application developed in Xamarin to control and customize the prosthesis. The project was conducted in collaboration with 3D Ingeniería BQ and Universidad de la Costa in Barranquilla, Colombia. The prototype enables detecting and processing electromyographic (EMG) signals to control essential functions like grasping and typing, which are crucial for users’ daily activities. In trials conducted with 50 users, results demonstrated high satisfaction regarding movement accuracy, ease of application use, and overall satisfaction. Additionally, it positively evaluated the system's robustness and effectiveness in replicating movements. These findings suggest that the prototype is functionally effective and economically accessible, offering a viable and competitive alternative to expensive commercial prostheses. The application of open-source technologies and 3D printing significantly reduces development costs and facilitates customization and continuous improvement of the device. This approach allows access to functional and low-cost prostheses, improving the quality of life for individuals with disabilities worldwide.