This chapter presents a selection of best practices alongside pragmatic research projects to illustrate how design and designers played a strategic role in supporting the third sector organisations in their innovation processes. The empirical research activities bring rich first-hand data and in-person experience. These cases and research projects are illustrated in detail for an in-depth investigation of how the previously developed theories change, how the previously created methods and tools should be adapted, and how the experiences with the third sector organisation enable strategic design and design management domains to redefine their ways of thinking and doing.