Cartilage lesions are common and have a finite ability to repair and regenerate due to the lack of blood, nerve, and lymph supplies. Current treatments employing biomaterials for cartilage regeneration are of limited effectiveness since most of them have to be shaped externally before introduction to the body. Also, implantation often requires open incisions, increasing the risk of infection and patient discomfort. Therefore, finding a favorable therapy to treat cartilage damage is imperative before joints are irritated further. During transplantation, stem cells should be encapsulated in the biocompatible matrix to prevent their death at the injury site, and further regeneration requires a combination of stem cells, scaffolds, and bioactive signals, also known as the triad of tissue engineering. Injectable hydrogels, playing as three-dimensional scaffolds, can support cell proliferation and regeneration of damaged tissues. Amongst them, self-crosslinking hydrogels, without the use of regular mass crosslinking agents, not only ensure non-toxicity for stem cells but also are an encouraging resolution for establishing injectable scaffolds. Among different in situ-crosslinking mechanisms, Schiff base linkage between amino and aldehyde groups is a potential manner for fabricating self-crosslinking hydrogels. Moreover, various natural biopolymers used for fabricating hydrogel can provide abundant functional groups to facilitate intra-network self-crosslinking establishment and mimic the extracellular matrix to promote stem cell adhesion, proliferation, and differentiation. Therefore, self-crosslinking hydrogels emerge as promising bioinks in cartilage tissue bioprinting. Following the general bioprinting process, the prepared hydrogel precursor/s (with cell addition) are put in a syringe or nozzle of the bioprinter and dispersed over the platform along the route directed by the proposed model at temperatures ranging from 0 ℃ to 90 ℃ (usually body temperature). Finally, self-crosslinking hydrogels form mechanically stable structures, which are then characterized to ensure their validity for later applications.