Health and health systems have been undergoing rapid changes in recent years. Digital health, using information and communication technologies in the health system, is a crucial building block for universal health coverage and achieving health-related Sustainable Development Goals. However, to develop its full potential, the individual aspects of the digital health governance structure must be known, and the appropriate governance structures should be accompanied by mechanisms for equitable, sustainable, and high-quality health systems. The World Health Organization has identified six building blocks of a health system (service delivery, health workforce, health information systems, access to essential medicines, financing, and leadership/governance) for strengthening health systems, forming the basis for digital health governance. They must naturally be combined with the core elements of good governance (transparency, accountability, participation, integrity, and capacity). Using both analytical frameworks to analyze the state of digital health governance in Germany, for example, we get a first impression of where Germany stands in digitizing its health system. That information is essential, as health systems worldwide are increasingly faced with digitalization and digital transformation. Thus developing and providing strong governance, as exemplified in this chapter, will be necessary to harvest benefits and reduce unnecessary errors and negative trends worldwide health systems may take.