Migrants make an important contribution to the historical formation and identity of Latin America. Over time, a culture of hospitality has been established and cultivated in the region. This fact does not exclude contradictions and ambiguities regarding migration ethics there. This chapter presents the main facts that have marked the history of migration in Latin America, particularly in South America including both voluntary and forced migration. There have been different developments in the perceptions and treatments of both types of migration because international law and the international organisations mandated to deal with the issue (UNHCR, IOM, OAS) have developed different regimes and levels of commitments and obligations towards them. Although international, regional and human rights organisations have claimed that a human rights approach is applied to migrants in general, a broad concept of forced migration, including the right to asylum, protection policies and refugee integration, has seen a peculiar development in Latin America, with a more profound impact on migration ethics. In this regard, the notion of “solidarity” was expressed and adopted in the Cartagena Regime applied for refugees in the region. This paper is divided into six sections: (1) From Independence to World War II; (2) The OAS and the 1951 Geneva Convention; (3) The Cold War (1947–1989), the Emergence of Authoritarian Regimes and their Impacts on Migration; (4) From the Post-Cold War Era to the Era of the War on Terror (1990/2001–); (5) Contemporary Issues Concerning Globalisation, Regionalism, Migration and Its Contradictions; (6) Future Research, Relevance for Current Migration Ethics.