In many industries, there is a growing need for lightweight structures that can endure a wide array of loads. To address this need, the common strategy involves using architectural sandwiches, where two outer skins are bonded to a central core. These cores are known for their structural flexibility, with each design offering unique mechanical properties suited for different industrial applications. This study examines three sandwich structures made with 3D-printed cores featuring conventional honeycomb, rectangular, and re-entrant honeycomb designs. The cores are printed from a bio-based material, polylactic acid (PLA), using a Raise3D E2 printer. The fabricated specimens undergo tensile testing with varying printing orientations. Key findings reveal that printing orientation significantly affects Young's modulus and tensile yield strength. The goal is to investigate how different core designs impact the bending behavior of additively manufactured sandwich structures. Three-point bending tests are performed to assess the bending characteristics of these structures made from biodegradable PLA.