Toxic heavy metals from anthropogenic activities are the primary source of environmental pollutants and have a profound negative impact on the biotic and abiotic components of the environment through their non-degradability and persistence in nature. The costs of conventional remediation methods for such contaminants are often high and inefficient. Using biosurfactants produced by microorganisms to remediate heavy metals is one of the environmentally sound alternative approaches. Biosurfactants can be complexed with metallic ions, which decreases their solution-phase activity in solution, thus promoting desorption. They enhance metal solubility, mobilization, and bioavailability and perform efficiently at various pH, temperatures, and salinity. Several studies have documented the importance of biosurfactants in the remediation of heavy metals, including cadmium, arsenic, cobalt, lead, chromium, nickel, copper, and zinc. Moreover, this technology offers an expectant and green solution to secondary contamination problems that could result from using chemical surfactants and chelating agents in conventional approaches.