The integration of bioinformatics and molecular biology has advanced the search for biomarkers in several diseases. In this study, we searched for possible microRNA biomarkers related to Ulcerative Colitis, a chronic and progressive immune-mediated inflammatory condition characterized by inflammation of the gastrointestinal tract. Starting from a set of public datasets, we collect a set of miRNAs and analyze the possible interactions between miRNAs, their target genes, and the associated enriched pathways, related in particular to inflammation and oxidative stress.