Blockchain technology has the potential to revolutionize supply chain management by providing secure, transparent, and efficient Decision Support Systems (DSS). This chapter explores the integration of blockchain technology into DSS to enhance the security, transparency, and efficiency of supply chain operations. This chapter aims to serve as a valuable resource for researchers, practitioners, and policymakers dedicated to improving supply chain management through blockchain technology. By providing a comprehensive overview of blockchain-based decision-support systems and their applications, this chapter seeks to inspire innovative approaches and drive advancements in creating secure, transparent, and efficient supply chains. The chapter will begin by addressing critical challenges in supply chain management, such as fraud, lack of transparency, and inefficiency. It will highlight how blockchain technology can address these issues by creating immutable and transparent records of transactions, thereby enhancing trust among stakeholders. The concept and architecture of blockchain-based DSS will be examined, detailing key components such as distributed ledgers, smart contracts, and consensus mechanisms. Diagrams will illustrate the interaction between these components and the flow of information within the system, showcasing how blockchain ensures data integrity and transparency. Effective data collection and integration are vital for the functionality of blockchain-based DSS. The chapter explores various data sources, including IoT devices, ERP systems, and external databases, discussing methodologies for ensuring seamless data integration and real-time updates within the blockchain framework.