The integration of artificial intelligence (AI) into telemedicine is transforming healthcare delivery. AI tools, such as machine learning and predictive analytics, are enhancing diagnostic precision, patient monitoring, and personalized treatment. These innovations improve access to care, especially in underserved areas, while reducing healthcare costs. However, the use of AI in telemedicine brings challenges like data privacy, algorithmic bias, and the risk of widening the digital divide. This chapter explores both the benefits and challenges of incorporating AI into virtual healthcare, highlighting its potential to reshape the future of patient care.