A coping mechanism is exclusively associated with health and well-being that prevails in every person, including healthy environments, responsive parenting, a sense of belonging, healthy activities, resilience, and treating illness. Therefore, health coping mechanisms are the practices and activities of a single day that make health better and prevent diseases, which are directly allied with physical and mental health. The theme of this chapter is the basic concept and methodology of health coping mechanisms of the urban poor. This chapter includes what we mean by health coping mechanisms with a review of past literature and geographical perspectives on the concept’s significance in the present era. This chapter also incorporated the study area with the primary data collection, methods, analysis, and representations we applied in the study with proper illustrations. Generally, we included geostatistic tools with GIS and remote sensing applications for the spatial distribution and modeling of present societal phenomena. Finally, this chapter highlights the significant limitations of conducting this type of study.