When is the first executive function identified? What are the early molecular building blocks of this first occurrence? What are the rhythms of their development on the vector of time, and how do they relate to overt early behavior? How do the molecular rhythms dictate morphological development up to elicitation of the first executive function? This chapter will address these questions. Recent views based on groundbreaking 3D, 4D ultrasonic recordings suggest that early executive functions are shown in human fetal behavior and that this rich repertoire does not occur abruptly when the newborn meets the out-uterine environment as previously thought. It is shown in this chapter that the genetic clocks of expression and suppression within the prefrontal-thalamic-hypothalamic-hippocampal-corticospinal tract network develop in a combinatorial time-sensitive manner into cortical ability to reach short states of awakening. Once these brief states have occurred, the alert state span may widen in later repetitions of this condition often described as a paradoxical alpha wave with the return of the alpha wave to the EEG pattern. Differential rates of growth in the different prefrontal growing systems occur in parallel with growth in lower regions coordinating prefrontal-thalamic-hypothalamic-hippocampal-corticospinal tract network. This chapter argues that cortical and subcortical regions develop as early structural volumes towards each other and their mutual embrace elicits the components of the alert state and more complex behavior phenomena later in gestation. These processes develop while residual physiological and cortical excitability, which follows the behavioral execution of a function, decreases from mid-gestation onward, showing more coordination of network wiring and feedback loops from the behavioral to the molecular level. While the molecular basis affording the occurrence of short alert states and aligned early fetal executive functions encompasses a time-sensitive mode of expression, mid-gestation is the time when genetic and cellular clocks are beginning to be shaped by experience. This suggests that at this time window any remaining differentiation starts to overlap with pruning processes. It is hypothesized that this transition around mid-gestation is afforded by changes in the earlier combinatorial balance between molecules which promote vs. those which restrict expression. Furthermore, this balance gradually changes on the genetic-driven level to respond to environmental inputs too, resembling the earlier shown capacity of clock genes. It is concluded that although the clocks of executive functions are based on early molecular building blocks, from mid-gestation onwards, this molecular basis interacts with the environment too, in a manner that any fetal acquisition of an executive function cannot be predicted by either the clocks or the environmental stimuli only.