The captive breeding and the reintroduction of threatened species are among the most challenging conservation interventions. To date, 23 globally threatened, endangered, and at-risk anuran species have been captive-bred and reintroduced. Of these 23 anuran species, 5 are tropical. Based on meta-analyses conducted since the late 1980s, translocation success of amphibians and herpetofauna is 14% lower on average than translocation success for mammals, birds, and combined taxa. This is very likely a result of the emergence of chytridiomycosis and its interaction with other risk factors including habitat loss, climate change, toxic compounds, and invasive species. Previous meta-analyses of terrestrial vertebrate taxa have also revealed that translocation success for many taxa is higher among (1) large than small populations; (2) wild-sourced than captive-bred populations; (3) populations translocated to the core of their historic range; (4) populations translocated to sites where habitat is good to excellent; and (5) soft than hard releases. This book describes the species recovery program that was designed and implemented to conserve the Kihansi Spray Toad Nectophrynoides asperginis an Afrotropical and extinct-in-the-wild species.