Upon activation, mast cells release an abundance of mediators that are involved in allergic pathways. These mediators include preformed mediators and newly formed lipid mediators, in addition to cytokines and chemokines. In this chapter, we will focus primarily on lipid mediators, the target of leukotriene modifiers.

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Leukotriene Modifiers for Recalcitrant Chronic Rhinosinusitis

  • Akaansha Ganju,
  • Vivian Wang,
  • Joseph Yusin

摘要

Upon activation, mast cells release an abundance of mediators that are involved in allergic pathways. These mediators include preformed mediators and newly formed lipid mediators, in addition to cytokines and chemokines. In this chapter, we will focus primarily on lipid mediators, the target of leukotriene modifiers.