Various imaging technologies, including radiographic imaging, panoramic imaging, computed tomography, handheld devices, and cone beam devices have been widely used in dental imaging. This chapter provides an overview of those imaging techniques and their related safety and quality issues. Radiation dose and image quality are examined, along with evaluations of potential risks and safety concerns. Quality assurance and quality control requirements are reviewed. Relevant regulations, guidelines, and regulatory bodies are discussed. The integration of AI tools that assist in diagnosing, decision-making, and treatment prognosis prediction is explored. Ongoing efforts to improve quality and patient safety are also discussed.