As quantum computing rapidly improves, an increasing number of businesses are considering a mix of blockchain technology and post-quantum cryptography to protect their secret data. The article investigates how technologies can yield a different level of security in health, as well as supply chain management, and improve the current dimension in banking systems. Using self-executing smart contracts, the technology brings better traceability and hence humanly transparent transactions. This helps with view of making supply lines hackproof. However, while there is the promise of much change, blockchain technology has issues regarding its energy use and scaling that could potentially hinder its wide-reaching deployment. Post-quantum cryptography can answer tough math problems that can help deal with the threats of quantum computing and, at the same time, be used to help in weakening pre-existent security systems. Thus, strong data security would require continuous improvement in existing and development in new cryptographic approaches. This article has presented the integration process of Blockchain and post cryptography and highlights integration opportunities, and challenges. It is important to deal with changing security needs and make sure that blockchain technology will still work in a world where quantum computing is common.