This introductory chapter frames tourism within a multidisciplinary research context, emphasizing the theoretical contributions of economic geography while acknowledging its limits. The book focuses on tourism-related questions where economic geography offers well-supported insights and also highlights areas requiring connections with other disciplines. The first part explores key concepts such as spatial allocation, agglomeration, specialization and path dependence, applying them to tourism. The second part reverses this approach, addressing tourism challenges—urban transformation, mobility, sustainability and governance—through an economic geography lens while identifying the need for interdisciplinary perspectives. The chapter also traces the evolution of tourism research, discussing the role of geography and economics and introducing frameworks from New Economic Geography (NEG) and Evolutionary Economic Geography (EEG). By outlining both the strengths and limitations of economic geography, this chapter sets the foundation for a structured examination of tourism within a broader research framework.