Synergy, as theorized by Richard Katz, provides a bold account of the ongoing value Indigenous approaches to psychology and healing have for practitioners working in mental health systems. In this concluding chapter, I argue that synergy is a powerful antidote to many of the most pressing challenges facing mental health systems that are struggling to meet demand and ensure sufficient care is provided to the most vulnerable clients. Mental health practitioners are on the front lines of a series of overlapping global and local crises, and innovative thinking is necessary if the mental health industry is to meet the growing demand brought on by climate change, systemic racism, global conflict, economic inequality, and the opioid crisis. By respectfully drawing on deep traditions of Indigenous knowledge and practice, synergy provides a way to bring clients and communities, practitioners and administrators, into a dynamic process of collaboration that unlocks the resources needed for healing.