This chapter explores key psychological frameworks in global health, emphasizing the interplay of individual, societal, and environmental factors in shaping health outcomes. Central to the discussion is the biopsychosocial model, which integrates biological, psychological, and social determinants to provide a holistic perspective on well-being. The chapter also examines social determinants of health—such as socioeconomic status, education, and cultural norms—and their role in shaping healthcare access and disparities. Highlighting the contributions of behavioral health psychology and psychosocial interventions, it underscores how psychological insights inform strategies for health promotion and disease prevention. Real-world examples illustrate the practical application of these concepts to health challenges, providing a foundation for understanding the intersections of psychology and global health.