Follow-up after thermal ablation of benign thyroid nodules should be performed at 1–3 months, 6-months, and 1-year after treatment. Clinical examination should assess for procedure-related complications and may be enhanced with tracking of symptom and cosmetic scores. Biochemical (TSH) assessment should also be performed, more frequently for autonomously functioning nodules, especially when titrating or weaning antithyroid medication. Ultrasound evaluation is a central component of follow-up. It is important to recognize that treated nodules may appear suspicious on ultrasound, and communicating the history of prior ablation to any new providers is crucial. Assessment of treatment efficacy may involve calculation of the volume reduction ratio (VRR), initial ablation ratio (IAR), or vital volume (Vv), as well as patient-reported outcomes; optimal means for assessing nodule regrowth and indications and timing for retreatment remain active areas of study.