Aims: The objective is to assess the biomechanical, organisational and psychological constraints and associated risks of musculoskeletal disorders (MSDs) among artisanal weavers. Participants and methodology: The initial phase entailed the collection of data concerning general health and the evaluation of organisational and psychosocial constraints within the workplace. The subsequent phase comprised a semi-quantitative analysis of biomechanical constraints, based on video recordings from five weaving workshops. Results: The total number of weavers included in the study was 20, with an average age of 61.33 ± 5.82 years. The average tenure was 38.1 ± 11.9 years. The data revealed that 30% of the time spent working by artisan weavers was spent in a shoulder flexion or abduction posture, with a variability of 54.1%. It was observed that 12.6% of their working time was spent in a visible state of adduction or rotation, with a variability of 22.3%. The analysis of wrist and hand movements revealed that 39.4% of the work time was spent in extension > 30°, with a variability of 53.7%. The data revealed that 53.7% of the working time was spent on digital gripping with a few fingers, with a variability of 53.2%. Conclusion: Despite the repetitive and highly variable nature of the movements, none of the weavers reported any musculoskeletal complaints or discomfort in the previous 12 months. These findings indicate that psychosocial and organisational aspects should be taken into account to ensure effective prevention of work-related musculoskeletal disorders in other industries.