Sustainable ergonomics is an interdisciplinary approach that combines principles from ergonomics (the study of designing workspaces for human well-being) and sustainability (the pursuit of environmental, social, and economic balance). Sustainable ergonomics plays a crucial role in achieving sustainable business, not only in large companies but also small and medium enterprises (SMEs) which play a vital role in employment and economic growth. However, when it comes to implementing sustainable ergonomics, SMEs face unique challenges including lack of awareness and reluctancy to adopt ergonomic and sustainable practices. Indonesia has over 62 million SMEs, which are considered crucial to Indonesia's economy, accounting for around 97% of employment. However, there is still lack of attention to the practice of ergonomics and sustainability in Indonesia’s SMEs. The focus of Indonesia’s SMEs is mainly on making profits to ensure the sustainable business from the economic aspect, not yet putting effort to achieve balance on the environmental and social aspects. When it comes to the implementation of sustainable ergonomics, many work systems in Indonesia’s SMEs are far from inevitable. This study aims to analyze and develop evaluation about sustainable work systems in 17 Indonesia’s SMEs in various sectors including craft, food, and textile. The measures of sustainable work index in these SMEs showed the need to improve the practice of sustainable ergonomics in their daily business and manufacturing practices. This calls for immediate actions that can be taken by business owners to increase the sustainable work index in these investigated SMEs. This research also provides suggestions of improvement for SME’s owner on how they can help their SMEs thrive and ensure sustainable ergonomics.