Reservoir sediment replaces clay and shale for the preparation of sintered bricks, which is of great significance to the country’s protection of cultivated land and mountains, exploration of new models of sediment utilization, and organic integration of high-quality regional social development. This paper systematically reveals the effects of different forming pressures, mix ratios, and sintering processes on the performance and microstructure of sintered bricks prepared from Zipingpu reservoir sediment. These results are capable of offering scientific backing for the multi-channel utilization of the sediment from Zipingpu reservoir. Research shows that a) For the Zipingpu reservoir sand sintered brick, the optimal preparation process parameters are as follows: the forming pressure is 600 kN, the sintering temperature is 925 °C, and the sintering time is 1 h. Under these conditions, the obtained sintered brick has a compressive strength of 29.64 MPa. b) The mineral components of the sintered products are quartz, plagioclase, potassium feldspar, pyroxene, and magnetite. Quartz and calcite in the sand decompose at high temperatures and react to form plagioclase and potassium feldspar. c) The infrared absorption peaks of sand and sintered bricks all appear near 3429 cm−1, 1632 cm−1, 1431 cm−1, 1023 cm−1, 767 cm−1, 530 cm−1, and 467 cm−1.