Tendon and ligament injuries are prevalent among both athletes and the elderly, often resulting in pain, joint instability, and potentially leading to conditions such as osteoarthritis or disability. Overcoming these challenges in therapeutic intervention remains complex due to the limited intrinsic regenerative capacity of these tissues. Consequently, tissue engineering has emerged as a promising approach to address these issues by replicating the natural extracellular matrix of tendons and ligaments, thereby restoring their structural integrity and physiological function. This chapter provides a concise overview of the anatomical and functional aspects of tendons and ligaments, including common injuries and current treatment modalities. Furthermore, it explores the application of bioinspired chemical, topological, and mechanical cues in tendons and ligaments tissue engineering. A comprehensive review of previous studies reveals various materials and biomimetic fabrication techniques utilized for creating biomimetic/bioinspired structures to closely resemble the native tissue microenvironment and facilitate effective regeneration. However, despite significant progress, the challenges persist in the development of biomimetic tendon and ligament structures, along with future prospects, are thoroughly discussed, providing valuable insights for researchers and practitioners in the field. This chapter aims to elucidate the principles underlying biomimetic/bioinspired materials and architecture for tendon and ligament repair, thereby guiding future research endeavors in this critical area of regenerative medicine.