The classification of DNA sequences remains a significant challenge for biologists seeking to analyze vast amounts of biological data. Artificial intelligence has emerged as a powerful tool for addressing this issue, revolutionizing healthcare in various ways. From developing new clinical systems to managing patient data and treating diseases, artificial intelligence techniques, such as machine learning and deep learning, are essential. The COVID-19 pandemic has highlighted the critical need for accurate and efficient disease identification. Machine learning approaches have proven invaluable in predicting COVID-19 infections. In this paper, we employed complete human gene sequences to differentiate COVID-19 (SARS-CoV-2) from other coronavirus strains. We utilized Long-Short-Term Memory (LSTM), Convolutional Neural Networks (CNN), and Autoencoder techniques for classification. Five models were proposed: CNN, LSTM, CNN-LSTM, AE-CNN, and AE-CNN-LSTM. Our hybrid AE-CNN-LSTM model demonstrated superior performance, achieving an overall accuracy of 99% in COVID-19 classification.

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A Hybrid Deep Learning Model Using CNN, LSTM and Auto Encoder to Predict Covid-19 from Human Genome

  • Noha El-Attar,
  • Bossy M. Moustafa,
  • Sami A. AbdelHafeez,
  • Wael A. Awad

摘要

The classification of DNA sequences remains a significant challenge for biologists seeking to analyze vast amounts of biological data. Artificial intelligence has emerged as a powerful tool for addressing this issue, revolutionizing healthcare in various ways. From developing new clinical systems to managing patient data and treating diseases, artificial intelligence techniques, such as machine learning and deep learning, are essential. The COVID-19 pandemic has highlighted the critical need for accurate and efficient disease identification. Machine learning approaches have proven invaluable in predicting COVID-19 infections. In this paper, we employed complete human gene sequences to differentiate COVID-19 (SARS-CoV-2) from other coronavirus strains. We utilized Long-Short-Term Memory (LSTM), Convolutional Neural Networks (CNN), and Autoencoder techniques for classification. Five models were proposed: CNN, LSTM, CNN-LSTM, AE-CNN, and AE-CNN-LSTM. Our hybrid AE-CNN-LSTM model demonstrated superior performance, achieving an overall accuracy of 99% in COVID-19 classification.