The transmission of power and motion is a fundamental problem in mechanical engineering, and this can be accomplished in many ways. A solution is to use transmissions with intermediate rolling elements (balls or rollers). In this context, the paper presents a modeling and simulation methodology of a mechanical power transmission with intermediate rolling elements (balls with radial movement) that allows transmission of power and motion between two coaxial shafts. The proposed transmission permits two configurations with different ratios between input and output by using the same geometry of its elements and a different number of rolling elements. To verify this, both configurations of the transmission were modeled, simulated and validated in SolidWorks by means of the motion analysis features of the CAD software. The methodology can be useful to understand how this type of transmission works.